Melissa McCarthy Reacts to Barbra Streisand Asking If She Uses Ozempic

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Melissa McCarthy tin instrumentality the heat. 

After Barbra Streisand brazenly questioned if she's been utilizing weight loss cause Ozempic, the Bridesmaids star seemed wholly unbothered.

"I deliberation Barbra is simply a treasure," Melissa told paparazzi April 30, "and I emotion her."

Just hours earlier, the Gilmore Girls alum shared a drawback to Instagram of her attending the Center Theater Group gala alongside director Adam Shankman.

"Pastels lone to grant the unthinkable @matthewbourne13 astatine the @ctgla gala past nighttime with this fella @adamshankman !!" she captioned the April 29 picture, which featured her strutting down the thoroughfare successful a pastel greenish dress, matching blazer and level heels. "Thiiiiis overmuch person to my imagination of dancing connected stage."

In a since-deleted comment on the post, Barbra gave her regards to Melissa's day for the evening earlier asking, "Did you instrumentality Ozempic?"

And it didn't instrumentality agelong for fans to catch wind of the 82-year-old's blunt comment, with galore adjacent rushing to come to Melissa's defense.

"Babs. No, honey," 1 idiosyncratic wrote nether the post. "Just no."

Others wondered if maybe Barbra had simply made a mistake. 

Photo by Alberto E. Rodriguez/Getty Images for Disney / Photo by Kevin Mazur/Getty Images for BSB

"Leave Barbara unsocial she would ne'er bash that connected purpose," another user commented. "I judge she meant that for a backstage question. Cant immoderate of you amusement her immoderate grace !!"

Barbra's reply aside, Melissa received tons of emotion connected the stunning photo, with stars similar Octavia Spencer, Glenn Close and Debby Ryan each gushing astir her ensemble successful the comments.

"GORGEOUS!!!" Glenn wrote, portion Octavia replied, "These lewks are yummy."

And this surely isn't the archetypal clip a prima has weighed successful on—or been accused of using—Ozempic. For each their comments connected Hollywood's latest craze, work on…

Presley Ann Photo / Shutterstock / Paul Archuleta / Getty Images

Jon Gosselin

The Jon & Kate Plus 8 alum told Page Six successful April 2024 that helium mislaid 32 pounds successful 2 months aft taking injections of semaglutide, the generic signifier of Ozempic.

"You cognize what's annoying?" helium said. "The regret of not starting it 10 years ago."

Nathan Congleton/NBC/NBCU Photo Bank via Getty Images

Ree Drummond

The Pioneer Woman prima shared connected her blog successful March 2024 that her 50-pound value nonaccomplishment successful 2022 was not owed to taking Ozempic oregon akin medications.

She added, "Not you'll ne'er perceive a 2nd of judgement from maine astir radical who take that direction!"

Todd Owyoung/NBC via Getty Images

Tracy Morgan

In August 2023, the 30 Rock alum said on Today With Hoda and Jenna that helium mislaid value connected Ozempic due to the fact that it supressed his appetite.

In March 2024, his wellness travel appeared to instrumentality a astonishing turn. "I've learned to out-eat Ozempic," helium said connected The Tonight Show Starring Jimmy Fallon. "I gained 40 pounds."

Later that month, helium clarified to E! News that helium was joking, adding, "Ozempic did large by maine and I was gladsome to usage it."

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Brooke Burke

“I can’t talk medically astir it, but I bash cognize that there’s truthful overmuch accusation astir what’s moving and what’s not,” she shared during portion of an interrogation with Fox News Digital. “I deliberation that Ozempic has immoderate large benefits, and I besides deliberation it has immoderate dangers.”

Gilbert Flores/Billboard via Getty Images

Tori Spelling

The Beverly Hills, 90210 tried the cause to assistance her slim down aft giving commencement to her son Beau successful 2017.

"I tried Ozempic and it didn't enactment for me," she shared successful an April 2024 occurrence of her misSPELLING podcast, "so I went connected Mounjaro, which did bash the instrumentality and I did suffer weight."

Aaron Poole/E! Entertainment/NBCU Photo Bank

Raven-Symoné

"I deliberation it's precise important we recognize definite medications are made for definite people," she told E! News' Francesca Amiker, "and to not instrumentality that distant conscionable for glamazon purposes."

Raven continued, "Do what you gotta do, conscionable marque definite you prevention the medicine for the radical who really request it."

Rodin Eckenroth/WireImage

Sharon Osbourne

The Talk U.K. big revealed successful September 2023 that she shed 42 pounds aft utilizing Ozempic earlier successful the year.

"Whatever you take is up to you," she exclusively told E! News. "It's not a soiled small concealed erstwhile you've taken thing to assistance you suffer weight, which is perfectly fine."

She added, "We don't person to bulls--t."

Instagram/Kelly Osbourne

Kelly Osbourne

Sharon's girl has besides weighed successful connected the Ozempic trend.

"I deliberation it's amazing," the Fashion Police alum told E! News successful January 2024. "There are a cardinal ways to suffer weight, wherefore not bash it done thing that's isn't arsenic boring arsenic moving out?"

John Nacion/Variety via Getty Images

Kate Winslet

The Titanic star, who was erstwhile a people for tabloids erstwhile it came to her weight, shared what she thought about the value nonaccomplishment trend.

"I really don't cognize what Ozempic is," Kate admitted to The New York Times Magazine in an interrogation published March 3. "All I cognize is that it's immoderate pill that radical are taking oregon thing similar that."

"Oh, my God," Kate remarked aft learning astir the drug. "This sounds terrible."

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Heidi Montag

The Hills prima revealed successful December 2023 that she'd precocious mislaid 22 pounds—without taking Ozempic. "There's nary shortcuts successful life. And if you're taking that shortcut, I don't know," she told Page Six of different celebrities utilizing the drug. "I don't privation to sanction names oregon get into it, it's conscionable thing I would ever do."

Heidi noted, "I privation thing that is sustainable. I privation thing that does besides necessitate hard work."

Charles Sykes/Bravo

Amy Schumer

The Trainwreck prima did not clasp backmost erstwhile she called retired celebrities for not being honorable astir utilizing Ozempic arsenic a value nonaccomplishment tool during her June 8, 2023 quality connected Watch What Happens Live. 

"Everyone and their ma is gonna effort it. Everyone has been lying saying, 'Oh, smaller portions,'" she told Andy Cohen, who has besides ppublicly weighed successful connected the Ozempic craze aggregate times. "Like, unopen the f--k up. You are connected Ozempic oregon 1 of those things, oregon you got enactment done. Just stop."

Schumer, who has been unfastened astir her past aesculapian procedures, added, "Be existent with people. When I got lipo, I said I got lipo."

She admitted to becoming "immediately invested" successful Ozempic past year, but explained that it was not "livable" for her to instrumentality the Type 2 diabetes cause and hindered her quality to walk clip with her 4-year-old lad Gene

"I was 1 of those radical that felt truthful sick and couldn't play with my son," Schumer recalled. "I was truthful skinny, and he's throwing a shot astatine maine and [I couldn't]."

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Dr. Drew Pinsky

"People person a mixed feeling astir interventions similar this," Dr. Drew exclusively told E! News astatine Fox's Special Forces: World's Toughest Test season 2 lawsuit successful Los Angeles connected Sept. 12, 2023. "They're tantalized by it, but connected the different hand, they person this weird judgment."

He continued, "If we person a medicine that tin beryllium helpful, by each means, radical should beryllium encouraged to deliberation astir it."

Jeff Spicer/Getty Images

Sophie Turner

Forget winter, a blistery instrumentality is coming.

The Game of Thrones alum was not shy when it came to sharing her sentiment about Ozempic and its advertisements.

In an April 5, 2023 Instagram Story, the histrion reposted a tweet from writer Sophie Vershbow that read, "The Ozempic ads plastered crossed the Times Square subway presumption tin f--k each the mode off." One ad featured successful Vershbow's Twitter photos read, "One changeable to suffer weight," portion different offered akin text, "A play changeable to suffer weight."

Turner adding her ain commentary, writing, "WTF."

Ozempic shaper Novo Nordisk antecedently told E! News that the cause is not FDA-approved for chronic value management.

"While we admit that immoderate healthcare providers whitethorn beryllium prescribing Ozempic for patients whose extremity is to suffer weight, Novo Nordisk does not promote, suggest, oregon promote off-label usage of our medicines and is committed to afloat complying with each applicable U.S. laws and regulations successful the promotion of our products," the Danish pharmaceutical institution said successful a statement. "We spot that healthcare providers are evaluating a patient's idiosyncratic needs and determining which medicine is close for that peculiar patient."

Mat Hayward/Variety via Getty Images

Chelsea Handler

Ozempic is nary laughing substance for the comedian. Handler revealed her "anti-aging doctor" prescribed her the medicine without realizing what the cause was.

"I didn't adjacent cognize I was connected it," she said during the Jan. 25, 2023 occurrence of Call Her Daddy. "She said, 'If you ever privation to driblet 5 pounds, this is good.'"

But portion she tried the drug, Handler noted that she didn't similar however it made her feel.

"I came backmost from a abrogation and I injected myself with it," she recalled. "I went to luncheon with a woman a fewer days later, and she was like, 'I'm not truly eating anything. I'm truthful nauseous, I'm connected Ozempic.' And I was like, 'I'm benignant of nauseous too.' But I had conscionable travel backmost from Spain and was jet-lagged."

Ultimately, Handler stopped utilizing the drug because it wasn't medically indispensable for her, adding that she gave distant the remaining doses to friends.

"I've injected astir 4 oregon 5 of my friends with Ozempic, due to the fact that I realized I didn't privation to usage it due to the fact that it was silly," she said. "It's for dense people. I person radical coming implicit to my house, and I'm like, 'OK, I tin spot you astatine 1, I tin spot you astatine 2.'"

Evan Agostini/AP/Shutterstock

Khloe Kardashian

KoKo clapped backmost erstwhile commenters connected Instagram speculated that she was taking Ozempic. 

"Let's not discredit my years of moving out," Kardashian wrote connected a January 2023 post. "I get up 5 days a week astatine 6am to train. Please halt with your assumptions. I conjecture caller twelvemonth inactive means mean people."

Trae Patton/E! Entertainment

Dr. Terry Dubrow

In summation to embracing the weight-loss drug, Dubrow really revealed successful January 2023 he temporarily utilized Mounjaro to larn however it affects the body.

"I thought it was amazing," the Botched prima shared. "I didn't person that overmuch value to lose. But I wanted to effort it due to the fact that truthful galore of my patients were connected it and I wanted to spot what it was similar erstwhile you're not diabetic and you lone person 10 to 15 pounds to lose."

Although Dr. Dubrow didn't disclose however overmuch value helium mislaid oregon however agelong helium took the medicine for, helium confirmed he's nary longer utilizing it.

"I thought, 'You cognize what, I benignant of privation to get my appetite back,'" helium explained the crushed for quitting the medication, noting helium besides experienced "low-grade nausea."

Ella Hovsepian/Getty Images

Kyle Richards

The Real Housewives of Beverly Hills prima got existent about claims that she was taking the medication aft her followers connected societal media took announcement of her value nonaccomplishment earlier this year.

Richards wrote backmost to 1 idiosyncratic nether a Jan. 5, 2023 drawback connected Instagram of herself and her girlfriends aft a workout, "I americium NOT connected ozempic." In different response, Richards added, "Never person been."

That wouldn't beryllium the past clip the Bravo prima changeable down the rumors, reiterating that she is "NOT taking" the medication under a Jan. 16 station connected Instagram by Page Six

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Jessica Simpson

After fans questioned whether oregon not she was taking Ozempic, Jessica acceptable the grounds straight.

Oh Lord," she told Bustle successful an interrogation published July 6, 2023. "I mean, it is not [Ozempic], it's willpower. I'm like, bash radical privation maine to beryllium drinking again? Because that's erstwhile I was heavier. Or they privation maine to beryllium having different baby? My assemblage can't bash it."

Trae Patton/E! Entertainment

Dr. Paul Nassif

Nassif echoed his Botched costar successful giving the cause 2 thumbs up.

"Just similar he's telling everyone, nary Ozempic-shaming," helium exclusively told E! News Feb. 1. "I'm OK with it. I'm OK with Terry and—actually a batch of my friends I saw this past weekend—they each look incredible. Health-wise, they felt better, their humor sugars came down, their humor unit came down. All of this tin hopefully assistance with longevity, you conscionable person to bash it the close way."

In fact, the famed integrative surgeon said taking Ozempic perchance has different benefits extracurricular of value management."We're looking into Ozempic much besides arsenic an anti-aging attraction for the future," Nassif explained. "So, there's going to hopefully beryllium immoderate bully things the much we larn astir each these semaglutides and the antithetic products. 

Paul Archuleta/Getty Images

Golnesa "GG" Gharachedaghi

This Shah isn't shy astir her Ozempic use. 

Gharachedaghi didn't "see a crushed to hide" being connected the medicine erstwhile discussing her wellness journey, telling Entertainment Tonight successful May 2023 that she would similar to "just speech astir it due to the fact that there's truthful galore radical retired determination who privation to bash the aforesaid happening oregon they privation to larn astir what you did."

Of her 30-pound value nonaccomplishment owed to her acquisition with Semaglutide—the generic mentation of the weight-loss drug—the Shahs of Sunset prima explained, "Obviously, I didn't look similar this 2 months ago. So..I would beryllium a liar to accidental I discontinue drinking intoxicant and you cognize each of a abrupt started moving retired similar immoderate radical similar to say."

Gharachedaghi went connected to enactment that she inactive has an appetite, saying, "I'm really a small hungry. Look I'm gonna spell fume a small cookware and I'm gonna devour definitely."

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Remi Bader

The influencer said that utilizing Ozempic to treat her benignant 2 diabetes negatively affected her wide health

"It was marque new, conscionable got FDA approved, nary 1 knew astir it and I was truthful scared," Bader recalled connected the Jan. 12, 2023 occurrence of the Not Skinny But Not Fat podcast. "They said I request this. And I had a batch of mixed feelings."

After she went disconnected the drug, Bader—who has been unfastened astir her conflict with binge eating—said it caused a rhythm of "bad binging."

"I saw a doctor, and they were like, 'It's 100 percent due to the fact that you went connected Ozempic,'" she explained. "It was making maine deliberation I wasn't bare for truthful long. I mislaid immoderate weight. I didn't privation to beryllium obsessed with being connected it agelong term. I was like, 'I stake the 2nd I got disconnected I'm going to get starving again.' I did, and my binging got truthful overmuch worse. So past I benignant of blamed Ozempic."

Arturo Holmes/FilmMagic

Dolores Catania

Forget shedding for the wedding due to the fact that The Real Housewives of New Jersey formed subordinate admitted she was taking Ozempic to suffer value anterior to filming the play 13 reunion. 

During the April 4, 2023 occurrence of Watch What Happens Live with Andy Cohen, Catania confirmed she had been taking the antidiabetic medicine due to the fact that she didn't privation to beryllium "looking immoderate bigger than anyone else," astatine the taping, explaining, "I got connected the bandwagon." She past joked that "not one" of her co-stars wasn't besides taking Ozempic and said the lone broadside effect she was experiencing was that she was "just not hungry."

Matt McNulty/Getty Images for ITF

Billie Jean King

The tennis legend—who has been unfastened astir her struggles with an eating disorder—expressed her reluctance successful trying diabetes medicine solely for value nonaccomplishment purposes. 

"With the caller injections, the Ozempics of the world, it's precise absorbing due to the fact that my doc wants maine to effort it," she shared successful an April 2024 occurrence of Lemonada Media's Wiser Than Me podcast. "I don't privation to suffer value accelerated due to the fact that I deliberation it looks horrible. I don't deliberation it's healthy."

However, she noted that she has "taken a fewer injections"

Instagram/Gracie McGraw

Gracie McGraw

Tim McGraw and Faith Hill's girl archetypal opened up astir taking the diabetes cause erstwhile she shared her PCOS diagnosis successful March 2022. 

"To get the close diagnosis you would request 2 retired of the 5 characteristics of PCOS and I had 4," she wrote connected Instagram astatine the time. "During my assignment with my endocrinologist I realized that whitethorn person been a origin successful my issues with weight, truthful we decided to effort a medicine to modulate my assemblage much usually and make the tools to proceed to support my assemblage and myself steadfast arsenic I get older."

Gracie offered an update connected her wellness journey successful a June 5 station aft a commenter called retired her alleged usage of Type 2 diabetes medication.

"I did usage Ozempic past year, yes," she wrote. "I americium present connected a debased dose of Mounjaro for my PCOS arsenic good arsenic moving out. No request to impeach erstwhile I person been unfastened astir it."

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